Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6

The transactive response DNA-binding protein (TARDBP/TDP-43) influences the processing of diverse transcripts, including that of histone deacetylase 6 (HDAC6). Here, we assessed TDP-43 activity in terms of regulating CD4+ T-cell permissivity to HIV-1 infection. We observed that overexpression of wt-...

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Detalles Bibliográficos
Autores principales: Cabrera-Rodríguez, Romina, Pérez-Yanes, Silvia, Montelongo, Rafaela, Lorenzo-Salazar, José M., Estévez-Herrera, Judith, García-Luis, Jonay, Íñigo-Campos, Antonio, Rubio-Rodríguez, Luis A., Muñoz-Barrera, Adrián, Trujillo-González, Rodrigo, Dorta-Guerra, Roberto, Casado, Concha, Pernas, María, Blanco, Julià, Flores, Carlos, Valenzuela-Fernández, Agustín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181786/
https://www.ncbi.nlm.nih.gov/pubmed/35682862
http://dx.doi.org/10.3390/ijms23116180

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