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Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment

The use of nanomaterials has been increasing in recent times, and they are widely used in industries such as cosmetics, drugs, food, water treatment, and agriculture. The rapid development of new nanomaterials demands a set of approaches to evaluate the potential toxicity and risks related to them....

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Autores principales: Lebre, Filipa, Chatterjee, Nivedita, Costa, Samantha, Fernández-de-Gortari, Eli, Lopes, Carla, Meneses, João, Ortiz, Luís, Ribeiro, Ana R., Vilas-Boas, Vânia, Alfaro-Moreno, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181910/
https://www.ncbi.nlm.nih.gov/pubmed/35683670
http://dx.doi.org/10.3390/nano12111810
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author Lebre, Filipa
Chatterjee, Nivedita
Costa, Samantha
Fernández-de-Gortari, Eli
Lopes, Carla
Meneses, João
Ortiz, Luís
Ribeiro, Ana R.
Vilas-Boas, Vânia
Alfaro-Moreno, Ernesto
author_facet Lebre, Filipa
Chatterjee, Nivedita
Costa, Samantha
Fernández-de-Gortari, Eli
Lopes, Carla
Meneses, João
Ortiz, Luís
Ribeiro, Ana R.
Vilas-Boas, Vânia
Alfaro-Moreno, Ernesto
author_sort Lebre, Filipa
collection PubMed
description The use of nanomaterials has been increasing in recent times, and they are widely used in industries such as cosmetics, drugs, food, water treatment, and agriculture. The rapid development of new nanomaterials demands a set of approaches to evaluate the potential toxicity and risks related to them. In this regard, nanosafety has been using and adapting already existing methods (toxicological approach), but the unique characteristics of nanomaterials demand new approaches (nanotoxicology) to fully understand the potential toxicity, immunotoxicity, and (epi)genotoxicity. In addition, new technologies, such as organs-on-chips and sophisticated sensors, are under development and/or adaptation. All the information generated is used to develop new in silico approaches trying to predict the potential effects of newly developed materials. The overall evaluation of nanomaterials from their production to their final disposal chain is completed using the life cycle assessment (LCA), which is becoming an important element of nanosafety considering sustainability and environmental impact. In this review, we give an overview of all these elements of nanosafety.
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spelling pubmed-91819102022-06-10 Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment Lebre, Filipa Chatterjee, Nivedita Costa, Samantha Fernández-de-Gortari, Eli Lopes, Carla Meneses, João Ortiz, Luís Ribeiro, Ana R. Vilas-Boas, Vânia Alfaro-Moreno, Ernesto Nanomaterials (Basel) Review The use of nanomaterials has been increasing in recent times, and they are widely used in industries such as cosmetics, drugs, food, water treatment, and agriculture. The rapid development of new nanomaterials demands a set of approaches to evaluate the potential toxicity and risks related to them. In this regard, nanosafety has been using and adapting already existing methods (toxicological approach), but the unique characteristics of nanomaterials demand new approaches (nanotoxicology) to fully understand the potential toxicity, immunotoxicity, and (epi)genotoxicity. In addition, new technologies, such as organs-on-chips and sophisticated sensors, are under development and/or adaptation. All the information generated is used to develop new in silico approaches trying to predict the potential effects of newly developed materials. The overall evaluation of nanomaterials from their production to their final disposal chain is completed using the life cycle assessment (LCA), which is becoming an important element of nanosafety considering sustainability and environmental impact. In this review, we give an overview of all these elements of nanosafety. MDPI 2022-05-25 /pmc/articles/PMC9181910/ /pubmed/35683670 http://dx.doi.org/10.3390/nano12111810 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lebre, Filipa
Chatterjee, Nivedita
Costa, Samantha
Fernández-de-Gortari, Eli
Lopes, Carla
Meneses, João
Ortiz, Luís
Ribeiro, Ana R.
Vilas-Boas, Vânia
Alfaro-Moreno, Ernesto
Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment
title Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment
title_full Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment
title_fullStr Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment
title_full_unstemmed Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment
title_short Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment
title_sort nanosafety: an evolving concept to bring the safest possible nanomaterials to society and environment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181910/
https://www.ncbi.nlm.nih.gov/pubmed/35683670
http://dx.doi.org/10.3390/nano12111810
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