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Synthesis and Antiproliferative Activity of Novel Dehydroabietic Acid-Chalcone Hybrids

Dehydroabietic Acid (DHA, 1) derivatives are known for their antiproliferative properties, among others. In the context of this work, DHA was initially modified to two key intermediates bearing a C18 methyl ester, a phenol moiety at C12, and an acetyl or formyl group at C13 position. These derivativ...

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Detalles Bibliográficos
Autores principales: Grigoropoulou, Sophia, Manou, Dimitra, Antoniou, Antonia I., Tsirogianni, Artemis, Siciliano, Carlo, Theocharis, Achilleas D., Athanassopoulos, Constantinos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181926/
https://www.ncbi.nlm.nih.gov/pubmed/35684559
http://dx.doi.org/10.3390/molecules27113623