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The Protective Effects of Neoastilbin on Monosodium Urate Stimulated THP-1-Derived Macrophages and Gouty Arthritis in Mice through NF-κB and NLRP3 Inflammasome Pathways

Gouty arthritis (GA) is a frequent inflammatory disease characterized by pain, swelling, and stiffness of joints. Neoastilbin is a flavonoid isolated from the rhizome of Smilax glabra, which possesses various anti-inflammatory effects. However, the mechanism of neoastilbin in treating GA has not yet...

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Detalles Bibliográficos
Autores principales: Xu, Wenjing, Li, Fenfen, Zhang, Xiaoxi, Wu, Chenxi, Wang, Yan, Yao, Yanjing, Xia, Daozong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181946/
https://www.ncbi.nlm.nih.gov/pubmed/35684415
http://dx.doi.org/10.3390/molecules27113477