Design, Synthesis, and In Vitro and In Vivo Antifungal Activity of Novel Triazoles Containing Phenylethynyl Pyrazole Side Chains

A series of triazole derivatives containing phenylethynyl pyrazole moiety as side chain were designed, synthesized, and most of them exhibited good in vitro antifungal activities. Especially, compounds 5k and 6c showed excellent in vitro activities against C. albicans (MIC = 0.125, 0.0625 μg/mL), C....

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Detalles Bibliográficos
Autores principales: Ni, Tingjunhong, Ding, Zichao, Xie, Fei, Hao, Yumeng, Bao, Junhe, Zhang, Jingxiang, Yu, Shichong, Jiang, Yuanying, Zhang, Dazhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182106/
https://www.ncbi.nlm.nih.gov/pubmed/35684308
http://dx.doi.org/10.3390/molecules27113370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182106/
https://www.ncbi.nlm.nih.gov/pubmed/35684308
http://dx.doi.org/10.3390/molecules27113370

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