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Recent Developments in the Photochemical Synthesis of Functionalized Imidazopyridines

Imidazopyridines constitute one of the most important scaffolds in medicinal chemistry, as their skeleton could be found in a myriad of biologically active molecules. Although numerous strategies were elaborated for imidazopyridine preparation in the 2010s, novel eco-compatible synthetic approaches...

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Autores principales: Tran, Christine, Hamze, Abdallah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182178/
https://www.ncbi.nlm.nih.gov/pubmed/35684399
http://dx.doi.org/10.3390/molecules27113461
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author Tran, Christine
Hamze, Abdallah
author_facet Tran, Christine
Hamze, Abdallah
author_sort Tran, Christine
collection PubMed
description Imidazopyridines constitute one of the most important scaffolds in medicinal chemistry, as their skeleton could be found in a myriad of biologically active molecules. Although numerous strategies were elaborated for imidazopyridine preparation in the 2010s, novel eco-compatible synthetic approaches have emerged, conscious of climate change concerns. In this framework, photochemical methods have been promoted to conceive this heterocyclic motif over the last decade. This review covers the recently published works on synthesizing highly functionalized imidazopyridines by light induction.
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spelling pubmed-91821782022-06-10 Recent Developments in the Photochemical Synthesis of Functionalized Imidazopyridines Tran, Christine Hamze, Abdallah Molecules Review Imidazopyridines constitute one of the most important scaffolds in medicinal chemistry, as their skeleton could be found in a myriad of biologically active molecules. Although numerous strategies were elaborated for imidazopyridine preparation in the 2010s, novel eco-compatible synthetic approaches have emerged, conscious of climate change concerns. In this framework, photochemical methods have been promoted to conceive this heterocyclic motif over the last decade. This review covers the recently published works on synthesizing highly functionalized imidazopyridines by light induction. MDPI 2022-05-27 /pmc/articles/PMC9182178/ /pubmed/35684399 http://dx.doi.org/10.3390/molecules27113461 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Tran, Christine
Hamze, Abdallah
Recent Developments in the Photochemical Synthesis of Functionalized Imidazopyridines
title Recent Developments in the Photochemical Synthesis of Functionalized Imidazopyridines
title_full Recent Developments in the Photochemical Synthesis of Functionalized Imidazopyridines
title_fullStr Recent Developments in the Photochemical Synthesis of Functionalized Imidazopyridines
title_full_unstemmed Recent Developments in the Photochemical Synthesis of Functionalized Imidazopyridines
title_short Recent Developments in the Photochemical Synthesis of Functionalized Imidazopyridines
title_sort recent developments in the photochemical synthesis of functionalized imidazopyridines
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182178/
https://www.ncbi.nlm.nih.gov/pubmed/35684399
http://dx.doi.org/10.3390/molecules27113461
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