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Screening a Panel of Topical Ophthalmic Medications against MMP-2 and MMP-9 to Investigate Their Potential in Keratoconus Management

Keratoconus (KC) is a serious disease that can affect people of any race or nationality, although the exact etiology and pathogenic mechanism are still unknown. In this study, thirty-two FDA-approved ophthalmic drugs were exposed to virtual screening using docking studies against both the MMP-2 and...

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Detalles Bibliográficos
Autores principales: Belal, Amany, Elanany, Mohamed A., Santali, Eman Y., Al-Karmalawy, Ahmed A., Aboelez, Moustafa O., Amin, Ali H., Abdellattif, Magda H., Mehany, Ahmed B. M., Elkady, Hazem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182209/
https://www.ncbi.nlm.nih.gov/pubmed/35684529
http://dx.doi.org/10.3390/molecules27113584