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A Drug–Drug Multicomponent Crystal of Metformin and Dobesilate: Crystal Structure Analysis and Hygroscopicity Property

A drug–drug multicomponent crystal consisting of metformin (MET) and dobesilate (DBS) was prospectively connected by solvent cooling and evaporating co-crystallization using the multicomponent crystal strategy, not only to optimize the physicochemical properties of single drugs, but also to play a r...

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Detalles Bibliográficos
Autores principales: Jiang, Lan, Hu, Xiangnan, Cai, Linhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182214/
https://www.ncbi.nlm.nih.gov/pubmed/35684409
http://dx.doi.org/10.3390/molecules27113472