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Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses
Spearmint (Mentha spicata L.) has been widely studied for its diversity of compounds for product generation. However, studies describing the chemical and biological characteristics of commercial spearmint materials from different origins are scarce. For this reason, this research aimed to bioprospec...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182276/ https://www.ncbi.nlm.nih.gov/pubmed/35684496 http://dx.doi.org/10.3390/molecules27113559 |
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author | Henao-Rojas, Juan Camilo Osorio, Edison Isaza, Stephanie Madronero-Solarte, Inés Amelia Sierra, Karina Zapata-Vahos, Isabel Cristina Betancur-Pérez, Jhon Fredy Arboleda-Valencia, Jorge W. Gallego, Adriana M. |
author_facet | Henao-Rojas, Juan Camilo Osorio, Edison Isaza, Stephanie Madronero-Solarte, Inés Amelia Sierra, Karina Zapata-Vahos, Isabel Cristina Betancur-Pérez, Jhon Fredy Arboleda-Valencia, Jorge W. Gallego, Adriana M. |
author_sort | Henao-Rojas, Juan Camilo |
collection | PubMed |
description | Spearmint (Mentha spicata L.) has been widely studied for its diversity of compounds for product generation. However, studies describing the chemical and biological characteristics of commercial spearmint materials from different origins are scarce. For this reason, this research aimed to bioprospecting spearmint from three origins: Colombia (Col), Mexico (Mex), and Egypt (Eg). We performed a biological activity analysis, such as FRAP, DPPH, and ABTS, inhibition potential of S. pyogenes, K. pneumoniae, E. coli, P. aeuroginosa, S. aureus, S aureus Methicillin-Resistant, and E. faecalis. Furthermore, we performed chemical assays, such as total polyphenol and rosmarinic acid, and untargeted metabolomics via HPLC-MS/MS. Finally, we developed a causality analysis to integrate biological activities with chemical analyses. We found significant differences between the samples for the total polyphenol and rosmarinic acid contents, FRAP, and inhibition analyses for Methicillin-Resistant S. aureus and E. faecalis. Also, clear metabolic differentiation was observed among the three commercial materials evaluated. These results allow us to propose data-driven uses for the three spearmint materials available in current markets. |
format | Online Article Text |
id | pubmed-9182276 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91822762022-06-10 Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses Henao-Rojas, Juan Camilo Osorio, Edison Isaza, Stephanie Madronero-Solarte, Inés Amelia Sierra, Karina Zapata-Vahos, Isabel Cristina Betancur-Pérez, Jhon Fredy Arboleda-Valencia, Jorge W. Gallego, Adriana M. Molecules Article Spearmint (Mentha spicata L.) has been widely studied for its diversity of compounds for product generation. However, studies describing the chemical and biological characteristics of commercial spearmint materials from different origins are scarce. For this reason, this research aimed to bioprospecting spearmint from three origins: Colombia (Col), Mexico (Mex), and Egypt (Eg). We performed a biological activity analysis, such as FRAP, DPPH, and ABTS, inhibition potential of S. pyogenes, K. pneumoniae, E. coli, P. aeuroginosa, S. aureus, S aureus Methicillin-Resistant, and E. faecalis. Furthermore, we performed chemical assays, such as total polyphenol and rosmarinic acid, and untargeted metabolomics via HPLC-MS/MS. Finally, we developed a causality analysis to integrate biological activities with chemical analyses. We found significant differences between the samples for the total polyphenol and rosmarinic acid contents, FRAP, and inhibition analyses for Methicillin-Resistant S. aureus and E. faecalis. Also, clear metabolic differentiation was observed among the three commercial materials evaluated. These results allow us to propose data-driven uses for the three spearmint materials available in current markets. MDPI 2022-05-31 /pmc/articles/PMC9182276/ /pubmed/35684496 http://dx.doi.org/10.3390/molecules27113559 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Henao-Rojas, Juan Camilo Osorio, Edison Isaza, Stephanie Madronero-Solarte, Inés Amelia Sierra, Karina Zapata-Vahos, Isabel Cristina Betancur-Pérez, Jhon Fredy Arboleda-Valencia, Jorge W. Gallego, Adriana M. Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses |
title | Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses |
title_full | Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses |
title_fullStr | Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses |
title_full_unstemmed | Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses |
title_short | Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses |
title_sort | towards bioprospection of commercial materials of mentha spicata l. using a combined strategy of metabolomics and biological activity analyses |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182276/ https://www.ncbi.nlm.nih.gov/pubmed/35684496 http://dx.doi.org/10.3390/molecules27113559 |
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