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Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach

Cholesterol is essential for normal human health, but elevations in its serum levels have led to the development of various complications, including hypercholesterolemia (HC). Cholesterol accumulation in blood circulation formsplaques on artery walls and worsens the individuals’ health. To overcome...

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Autores principales: Kumar, Harsh, Bhardwaj, Kanchan, Cruz-Martins, Natália, Sharma, Ruchi, Siddiqui, Shahida Anusha, Dhanjal, Daljeet Singh, Singh, Reena, Chopra, Chirag, Dantas, Adriana, Verma, Rachna, Dosoky, Noura S., Kumar, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182380/
https://www.ncbi.nlm.nih.gov/pubmed/35684416
http://dx.doi.org/10.3390/molecules27113479
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author Kumar, Harsh
Bhardwaj, Kanchan
Cruz-Martins, Natália
Sharma, Ruchi
Siddiqui, Shahida Anusha
Dhanjal, Daljeet Singh
Singh, Reena
Chopra, Chirag
Dantas, Adriana
Verma, Rachna
Dosoky, Noura S.
Kumar, Dinesh
author_facet Kumar, Harsh
Bhardwaj, Kanchan
Cruz-Martins, Natália
Sharma, Ruchi
Siddiqui, Shahida Anusha
Dhanjal, Daljeet Singh
Singh, Reena
Chopra, Chirag
Dantas, Adriana
Verma, Rachna
Dosoky, Noura S.
Kumar, Dinesh
author_sort Kumar, Harsh
collection PubMed
description Cholesterol is essential for normal human health, but elevations in its serum levels have led to the development of various complications, including hypercholesterolemia (HC). Cholesterol accumulation in blood circulation formsplaques on artery walls and worsens the individuals’ health. To overcome this complication, different pharmacological and non-pharmacological approaches are employed to reduce elevated blood cholesterol levels. Atorvastatin and rosuvastatin are the most commonly used drugs, but their prolonged use leads to several acute side effects. In recent decades, the potential benefit of ingesting yogurt on lipid profile has attracted the interest of researchers and medical professionals worldwide. This review aims to give an overview of the current knowledge about HC and the different therapeutic approaches. It also discusses the health benefits of yogurt consumption and highlights the overlooked phyto-enrichment option to enhance the yogurt’s quality. Finally, clinical studies using different phyto-enriched yogurts for HC management are also reviewed. Yogurt has a rich nutritional value, but its processing degrades the content of minerals, vitamins, and other vital constituents with beneficial health effects. The option of enriching yogurt with phytoconstituents has drawn a lot of attention. Different pre-clinical and clinical studies have provided new insights on their benefits on gut microbiota and human health. Thus, the yogurtphyto-enrichment with stanol and β-glucan have opened new paths in functional food industries and found healthy andeffective alternatives for HC all along with conventional treatment approaches.
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spelling pubmed-91823802022-06-10 Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach Kumar, Harsh Bhardwaj, Kanchan Cruz-Martins, Natália Sharma, Ruchi Siddiqui, Shahida Anusha Dhanjal, Daljeet Singh Singh, Reena Chopra, Chirag Dantas, Adriana Verma, Rachna Dosoky, Noura S. Kumar, Dinesh Molecules Review Cholesterol is essential for normal human health, but elevations in its serum levels have led to the development of various complications, including hypercholesterolemia (HC). Cholesterol accumulation in blood circulation formsplaques on artery walls and worsens the individuals’ health. To overcome this complication, different pharmacological and non-pharmacological approaches are employed to reduce elevated blood cholesterol levels. Atorvastatin and rosuvastatin are the most commonly used drugs, but their prolonged use leads to several acute side effects. In recent decades, the potential benefit of ingesting yogurt on lipid profile has attracted the interest of researchers and medical professionals worldwide. This review aims to give an overview of the current knowledge about HC and the different therapeutic approaches. It also discusses the health benefits of yogurt consumption and highlights the overlooked phyto-enrichment option to enhance the yogurt’s quality. Finally, clinical studies using different phyto-enriched yogurts for HC management are also reviewed. Yogurt has a rich nutritional value, but its processing degrades the content of minerals, vitamins, and other vital constituents with beneficial health effects. The option of enriching yogurt with phytoconstituents has drawn a lot of attention. Different pre-clinical and clinical studies have provided new insights on their benefits on gut microbiota and human health. Thus, the yogurtphyto-enrichment with stanol and β-glucan have opened new paths in functional food industries and found healthy andeffective alternatives for HC all along with conventional treatment approaches. MDPI 2022-05-28 /pmc/articles/PMC9182380/ /pubmed/35684416 http://dx.doi.org/10.3390/molecules27113479 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kumar, Harsh
Bhardwaj, Kanchan
Cruz-Martins, Natália
Sharma, Ruchi
Siddiqui, Shahida Anusha
Dhanjal, Daljeet Singh
Singh, Reena
Chopra, Chirag
Dantas, Adriana
Verma, Rachna
Dosoky, Noura S.
Kumar, Dinesh
Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach
title Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach
title_full Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach
title_fullStr Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach
title_full_unstemmed Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach
title_short Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach
title_sort phyto-enrichment of yogurt to control hypercholesterolemia: a functional approach
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182380/
https://www.ncbi.nlm.nih.gov/pubmed/35684416
http://dx.doi.org/10.3390/molecules27113479
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