A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines

We report a short synthetic route for synthesizing 2,3-substituted piperazine acetic acid esters. Optically pure amino acids were efficiently converted into 1,2-diamines that could be utilized to deliver the title 2,3-substituted piperazines in five steps with a high enantiomeric purity. The novel r...

Descripción completa

Detalles Bibliográficos
Autores principales: Chamakuri, Srinivas, Tang, Sunny Ann, Tran, Kevin A., Guduru, Shiva Krishna Reddy, Bolin, Peter K., MacKenzie, Kevin R., Young, Damian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182393/
https://www.ncbi.nlm.nih.gov/pubmed/35684357
http://dx.doi.org/10.3390/molecules27113419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182393/
https://www.ncbi.nlm.nih.gov/pubmed/35684357
http://dx.doi.org/10.3390/molecules27113419

Ejemplares similares