Exploring the Effect of Mechanical Anisotropy of Protein Structures in the Unfoldase Mechanism of AAA+ Molecular Machines

Essential cellular processes of microtubule disassembly and protein degradation, which span lengths from tens of [Formula: see text] m to nm, are mediated by specialized molecular machines with similar hexameric structure and function. Our molecular simulations at atomistic and coarse-grained scales...

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Detalles Bibliográficos
Autores principales: Varikoti, Rohith Anand, Fonseka, Hewafonsekage Yasan Y., Kelly, Maria S., Javidi, Alex, Damre, Mangesh, Mullen, Sarah, Nugent, Jimmie L., Gonzales, Christopher M., Stan, George, Dima, Ruxandra I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182431/
https://www.ncbi.nlm.nih.gov/pubmed/35683705
http://dx.doi.org/10.3390/nano12111849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182431/
https://www.ncbi.nlm.nih.gov/pubmed/35683705
http://dx.doi.org/10.3390/nano12111849

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