Whole-proteome structures shed new light on posttranslational modifications

Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily available proteomics results.

Detalles Bibliográficos
Autores principales: Joosten, Robbie P., Agirre, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182549/
https://www.ncbi.nlm.nih.gov/pubmed/35622853
http://dx.doi.org/10.1371/journal.pbio.3001673
Descripción
Sumario:Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily available proteomics results.

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