Whole-proteome structures shed new light on posttranslational modifications

Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily available proteomics results.

Detalles Bibliográficos
Autores principales: Joosten, Robbie P., Agirre, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182549/
https://www.ncbi.nlm.nih.gov/pubmed/35622853
http://dx.doi.org/10.1371/journal.pbio.3001673
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author Joosten, Robbie P.
Agirre, Jon
author_facet Joosten, Robbie P.
Agirre, Jon
author_sort Joosten, Robbie P.
collection PubMed
description Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily available proteomics results.
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spelling pubmed-91825492022-06-10 Whole-proteome structures shed new light on posttranslational modifications Joosten, Robbie P. Agirre, Jon PLoS Biol Primer Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily available proteomics results. Public Library of Science 2022-05-27 /pmc/articles/PMC9182549/ /pubmed/35622853 http://dx.doi.org/10.1371/journal.pbio.3001673 Text en © 2022 Joosten, Agirre https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Primer
Joosten, Robbie P.
Agirre, Jon
Whole-proteome structures shed new light on posttranslational modifications
title Whole-proteome structures shed new light on posttranslational modifications
title_full Whole-proteome structures shed new light on posttranslational modifications
title_fullStr Whole-proteome structures shed new light on posttranslational modifications
title_full_unstemmed Whole-proteome structures shed new light on posttranslational modifications
title_short Whole-proteome structures shed new light on posttranslational modifications
title_sort whole-proteome structures shed new light on posttranslational modifications
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182549/
https://www.ncbi.nlm.nih.gov/pubmed/35622853
http://dx.doi.org/10.1371/journal.pbio.3001673
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