Formulation of Polymers-Based Methotrexate Patches and Investigation of the Effect of Various Penetration Enhancers: In Vitro, Ex Vivo and In Vivo Characterization

The present study aimed to prepare methotrexate-loaded transdermal patches with different blends of hydrophobic and hydrophilic polymers (Eudragit S-100 and hydroxypropyl methylcellulose) at different concentrations. The polymers employed in transdermal patches formulations served as controlled agen...

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Detalles Bibliográficos
Autores principales: Latif, Muhammad Shahid, Nawaz, Asif, Rashid, Sheikh Abdur, Akhlaq, Muhammad, Iqbal, Asif, Khan, Muhammad Jamil, Khan, Muhammad Shuaib, Lim, Vuanghao, Alfatama, Mulham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182619/
https://www.ncbi.nlm.nih.gov/pubmed/35683883
http://dx.doi.org/10.3390/polym14112211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182619/
https://www.ncbi.nlm.nih.gov/pubmed/35683883
http://dx.doi.org/10.3390/polym14112211

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