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Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis

Background: The Global Leadership Initiative on Malnutrition (GLIM) criteria were recently proposed to build a global consensus on the diagnostic criteria for malnutrition. This study aimed to evaluate the GLIM criteria for its prognostic significance in outpatients with heart failure (HF), and to c...

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Autores principales: Joaquín, Clara, Alonso, Nuria, Lupón, Josep, Gastelurrutia, Paloma, Pérez-Monstesdeoca, Alejandra, Domingo, Mar, Zamora, Elisabet, Socias, Guillem, Ramos, Analía, Bayes-Genis, Antoni, Puig-Domingo, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182728/
https://www.ncbi.nlm.nih.gov/pubmed/35684044
http://dx.doi.org/10.3390/nu14112244
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author Joaquín, Clara
Alonso, Nuria
Lupón, Josep
Gastelurrutia, Paloma
Pérez-Monstesdeoca, Alejandra
Domingo, Mar
Zamora, Elisabet
Socias, Guillem
Ramos, Analía
Bayes-Genis, Antoni
Puig-Domingo, Manel
author_facet Joaquín, Clara
Alonso, Nuria
Lupón, Josep
Gastelurrutia, Paloma
Pérez-Monstesdeoca, Alejandra
Domingo, Mar
Zamora, Elisabet
Socias, Guillem
Ramos, Analía
Bayes-Genis, Antoni
Puig-Domingo, Manel
author_sort Joaquín, Clara
collection PubMed
description Background: The Global Leadership Initiative on Malnutrition (GLIM) criteria were recently proposed to build a global consensus on the diagnostic criteria for malnutrition. This study aimed to evaluate the GLIM criteria for its prognostic significance in outpatients with heart failure (HF), and to compare them to a previous validated method, such as the Mini Nutritional Assessment (MNA). Methods: This was a post hoc observational analysis of a prospectively recruited cohort, which included 151 subjects that attended an outpatient HF clinic. At baseline, all patients completed the nutritional screening MNA short form and the nutritional assessment MNA. In a post hoc analysis, we evaluated the GLIM criteria at baseline. The outcomes were based on data from a five-year follow-up. The primary endpoint was all-cause mortality. Secondary endpoints were cardiovascular (CV) mortality and recurrent HF-related hospitalizations. We also investigated whether the GLIM criteria had better prognostic power than the MNA. Results: Abnormal nutritional status was identified in 19.8% of the patients with the GLIM criteria and in 25.1% with the MNA. In the multivariate analyses (age, sex, NYHA functional class, diabetes, and Barthel index), nutritional status assessed by the MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalizations during the five-year follow-up. Conclusions: Malnutrition assessed by MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalization in our cohort of outpatients with HF.
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spelling pubmed-91827282022-06-10 Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis Joaquín, Clara Alonso, Nuria Lupón, Josep Gastelurrutia, Paloma Pérez-Monstesdeoca, Alejandra Domingo, Mar Zamora, Elisabet Socias, Guillem Ramos, Analía Bayes-Genis, Antoni Puig-Domingo, Manel Nutrients Article Background: The Global Leadership Initiative on Malnutrition (GLIM) criteria were recently proposed to build a global consensus on the diagnostic criteria for malnutrition. This study aimed to evaluate the GLIM criteria for its prognostic significance in outpatients with heart failure (HF), and to compare them to a previous validated method, such as the Mini Nutritional Assessment (MNA). Methods: This was a post hoc observational analysis of a prospectively recruited cohort, which included 151 subjects that attended an outpatient HF clinic. At baseline, all patients completed the nutritional screening MNA short form and the nutritional assessment MNA. In a post hoc analysis, we evaluated the GLIM criteria at baseline. The outcomes were based on data from a five-year follow-up. The primary endpoint was all-cause mortality. Secondary endpoints were cardiovascular (CV) mortality and recurrent HF-related hospitalizations. We also investigated whether the GLIM criteria had better prognostic power than the MNA. Results: Abnormal nutritional status was identified in 19.8% of the patients with the GLIM criteria and in 25.1% with the MNA. In the multivariate analyses (age, sex, NYHA functional class, diabetes, and Barthel index), nutritional status assessed by the MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalizations during the five-year follow-up. Conclusions: Malnutrition assessed by MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalization in our cohort of outpatients with HF. MDPI 2022-05-27 /pmc/articles/PMC9182728/ /pubmed/35684044 http://dx.doi.org/10.3390/nu14112244 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Joaquín, Clara
Alonso, Nuria
Lupón, Josep
Gastelurrutia, Paloma
Pérez-Monstesdeoca, Alejandra
Domingo, Mar
Zamora, Elisabet
Socias, Guillem
Ramos, Analía
Bayes-Genis, Antoni
Puig-Domingo, Manel
Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis
title Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis
title_full Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis
title_fullStr Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis
title_full_unstemmed Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis
title_short Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis
title_sort nutritional status according to the glim criteria in patients with chronic heart failure: association with prognosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182728/
https://www.ncbi.nlm.nih.gov/pubmed/35684044
http://dx.doi.org/10.3390/nu14112244
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