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Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis
Background: The Global Leadership Initiative on Malnutrition (GLIM) criteria were recently proposed to build a global consensus on the diagnostic criteria for malnutrition. This study aimed to evaluate the GLIM criteria for its prognostic significance in outpatients with heart failure (HF), and to c...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182728/ https://www.ncbi.nlm.nih.gov/pubmed/35684044 http://dx.doi.org/10.3390/nu14112244 |
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author | Joaquín, Clara Alonso, Nuria Lupón, Josep Gastelurrutia, Paloma Pérez-Monstesdeoca, Alejandra Domingo, Mar Zamora, Elisabet Socias, Guillem Ramos, Analía Bayes-Genis, Antoni Puig-Domingo, Manel |
author_facet | Joaquín, Clara Alonso, Nuria Lupón, Josep Gastelurrutia, Paloma Pérez-Monstesdeoca, Alejandra Domingo, Mar Zamora, Elisabet Socias, Guillem Ramos, Analía Bayes-Genis, Antoni Puig-Domingo, Manel |
author_sort | Joaquín, Clara |
collection | PubMed |
description | Background: The Global Leadership Initiative on Malnutrition (GLIM) criteria were recently proposed to build a global consensus on the diagnostic criteria for malnutrition. This study aimed to evaluate the GLIM criteria for its prognostic significance in outpatients with heart failure (HF), and to compare them to a previous validated method, such as the Mini Nutritional Assessment (MNA). Methods: This was a post hoc observational analysis of a prospectively recruited cohort, which included 151 subjects that attended an outpatient HF clinic. At baseline, all patients completed the nutritional screening MNA short form and the nutritional assessment MNA. In a post hoc analysis, we evaluated the GLIM criteria at baseline. The outcomes were based on data from a five-year follow-up. The primary endpoint was all-cause mortality. Secondary endpoints were cardiovascular (CV) mortality and recurrent HF-related hospitalizations. We also investigated whether the GLIM criteria had better prognostic power than the MNA. Results: Abnormal nutritional status was identified in 19.8% of the patients with the GLIM criteria and in 25.1% with the MNA. In the multivariate analyses (age, sex, NYHA functional class, diabetes, and Barthel index), nutritional status assessed by the MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalizations during the five-year follow-up. Conclusions: Malnutrition assessed by MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalization in our cohort of outpatients with HF. |
format | Online Article Text |
id | pubmed-9182728 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91827282022-06-10 Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis Joaquín, Clara Alonso, Nuria Lupón, Josep Gastelurrutia, Paloma Pérez-Monstesdeoca, Alejandra Domingo, Mar Zamora, Elisabet Socias, Guillem Ramos, Analía Bayes-Genis, Antoni Puig-Domingo, Manel Nutrients Article Background: The Global Leadership Initiative on Malnutrition (GLIM) criteria were recently proposed to build a global consensus on the diagnostic criteria for malnutrition. This study aimed to evaluate the GLIM criteria for its prognostic significance in outpatients with heart failure (HF), and to compare them to a previous validated method, such as the Mini Nutritional Assessment (MNA). Methods: This was a post hoc observational analysis of a prospectively recruited cohort, which included 151 subjects that attended an outpatient HF clinic. At baseline, all patients completed the nutritional screening MNA short form and the nutritional assessment MNA. In a post hoc analysis, we evaluated the GLIM criteria at baseline. The outcomes were based on data from a five-year follow-up. The primary endpoint was all-cause mortality. Secondary endpoints were cardiovascular (CV) mortality and recurrent HF-related hospitalizations. We also investigated whether the GLIM criteria had better prognostic power than the MNA. Results: Abnormal nutritional status was identified in 19.8% of the patients with the GLIM criteria and in 25.1% with the MNA. In the multivariate analyses (age, sex, NYHA functional class, diabetes, and Barthel index), nutritional status assessed by the MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalizations during the five-year follow-up. Conclusions: Malnutrition assessed by MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalization in our cohort of outpatients with HF. MDPI 2022-05-27 /pmc/articles/PMC9182728/ /pubmed/35684044 http://dx.doi.org/10.3390/nu14112244 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Joaquín, Clara Alonso, Nuria Lupón, Josep Gastelurrutia, Paloma Pérez-Monstesdeoca, Alejandra Domingo, Mar Zamora, Elisabet Socias, Guillem Ramos, Analía Bayes-Genis, Antoni Puig-Domingo, Manel Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis |
title | Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis |
title_full | Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis |
title_fullStr | Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis |
title_full_unstemmed | Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis |
title_short | Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure: Association with Prognosis |
title_sort | nutritional status according to the glim criteria in patients with chronic heart failure: association with prognosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182728/ https://www.ncbi.nlm.nih.gov/pubmed/35684044 http://dx.doi.org/10.3390/nu14112244 |
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