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Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins

Selenof (15-kDa selenoprotein; Sep15) is an endoplasmic reticulum (ER)-resident thioredoxin-like oxidoreductase that occurs in a complex with UDP-glucose:glycoprotein glucosyltransferase. We found that Selenof deficiency in mice leads to elevated levels of non-functional circulating plasma immunoglo...

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Detalles Bibliográficos
Autores principales:	Yim, Sun Hee, Everley, Robert A., Schildberg, Frank A., Lee, Sang-Goo, Orsi, Andrea, Barbati, Zachary R., Karatepe, Kutay, Fomenko, Dmitry E., Tsuji, Petra A., Luo, Hongbo R., Gygi, Steven P., Sitia, Roberto, Sharpe, Arlene H., Hatfield, Dolph L., Gladyshev, Vadim N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9183203/ https://www.ncbi.nlm.nih.gov/pubmed/29719252 http://dx.doi.org/10.1016/j.celrep.2018.04.009

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