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Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain

SNAREs are undoubtedly one of the core elements of synaptic transmission. Contrary to the well characterized function of their SNARE domains bringing the plasma and vesicular membranes together, the level of contribution of their juxtamembrane domain (JMD) and the transmembrane domain (TMD) to the v...

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Detalles Bibliográficos
Autores principales: Vardar, Gülçin, Salazar-Lázaro, Andrea, Zobel, Sina, Trimbuch, Thorsten, Rosenmund, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9183232/
https://www.ncbi.nlm.nih.gov/pubmed/35638903
http://dx.doi.org/10.7554/eLife.78182