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Systemic Maternal Human sFLT1 Overexpression Leads to an Impaired Foetal Brain Development of Growth-Restricted Foetuses upon Experimental Preeclampsia

The pregnancy disorder preeclampsia (PE) is characterized by maternal hypertension, increased level of circulating antiangiogenic soluble fms-like tyrosine kinase-1 (sFLT1), and reduced placental perfusion, leading to foetal growth restriction (FGR) and preterm birth. All these adverse effects are a...

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Detalles Bibliográficos
Autores principales: Vogtmann, Rebekka, Burk, Lilo Valerie, Serdar, Meray, Kimmig, Rainer, Bendix, Ivo, Gellhaus, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184195/
https://www.ncbi.nlm.nih.gov/pubmed/35693702
http://dx.doi.org/10.1155/2022/3024032

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