Cargando…

SARS-CoV-2: Molecular Structure, Pathogenesis, Potential Therapeutic Targets, and Immune Response of the Infected Subject

BACKGROUND: The pathogenic mechanisms and immune response of COVID-19 are far from clear. Through a documentary review of literature, the authors describe virological and molecular aspects of SARS-CoV-2, the intimate mechanisms of cell infection, and potential therapeutic targets. They also analyze...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wumba, R., Mandina, M., Nlandu, Y., Makulo, J. R., Tshimpi, A., Mbala, P., Mbangama, A., Kabututu, P., Kayembe, J. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184234/ https://www.ncbi.nlm.nih.gov/pubmed/35694045 http://dx.doi.org/10.1155/2022/7856659

Ejemplares similares

SARS-CoV2 mutations and impact on mortality: observational study in a sub-saharan Africa hospital
por: Makulo, Jean-Robert, et al.
Publicado: (2023)

SARS-CoV2 infection in symptomatic patients: interest of serological tests and predictors of mortality: experience of DR Congo
por: Makulo, Jean-Robert, et al.
Publicado: (2022)

Epidemiology of ebolavirus disease (EVD) and occupational EVD in health care workers in Sub-Saharan Africa: Need for strengthened public health preparedness
por: Ngatu, Nlandu Roger, et al.
Publicado: (2017)

Genital prolapse: epidemiology, clinic and therapeutic at Saint Joseph Hospital of Kinshasa
por: Kayembe, Antoine Tshimbundu, et al.
Publicado: (2020)

Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis
por: Bepouka, Ben, et al.
Publicado: (2022)

Factors associated with death in COVID-19 patients over 60 years of age at Kinshasa University Hospital, Democratic Republic of Congo (DRC)
por: Bepouka, Ben, et al.
Publicado: (2022)

WCN23-1156 INCIDENCE RATE OF COVID-19 HEMODIALYSIS UNIT ADMISSION AMONG CONGOLESE PATIENTS: EXPERIENCE DURING THE FIRST 4 WAVES OF THE PANDEMIC
por: Nlandu Mayamba, Y., et al.
Publicado: (2023)

Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.
por: Schäfer, Alexandra, et al.
Publicado: (2021)

Response to single dose hepatitis B vaccine in Congolese non-HIV hemodialysis patients: a prospective observational study
por: Kengibe, Pitchou Yemasai, et al.
Publicado: (2019)

Rubella Seroprevalence and real-time PCR detection of RUBV among Congolese pregnant women
por: Zanga, Josue, et al.
Publicado: (2017)

Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice
por: Schäfer, Alexandra, et al.
Publicado: (2022)

SARS Coronavirus Pathogenesis and Therapeutic Treatment Design
por: Sheahan, Timothy P., et al.
Publicado: (2009)

Animal models for SARS-CoV-2 and SARS-CoV-1 pathogenesis, transmission and therapeutic evaluation
por: Saravanan, Udhaya Bharathy, et al.
Publicado: (2022)

SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development
por: Zhou, Shilin, et al.
Publicado: (2023)

Implications of Sex Differences in Immunity for SARS-CoV-2 Pathogenesis and Design of Therapeutic Interventions
por: Bunders, Madeleine J., et al.
Publicado: (2020)

SARS-CoV-2: Pathogenesis, Molecular Targets and Experimental Models
por: Kanimozhi, G., et al.
Publicado: (2021)

Enterocytozoon bieneusi Identification Using Real-Time Polymerase Chain Reaction and Restriction Fragment Length Polymorphism in HIV-Infected Humans from Kinshasa Province of the Democratic Republic of Congo
por: Wumba, Roger, et al.
Publicado: (2012)

Interactions between malaria and HIV infections in pregnant women: a first report of the magnitude, clinical and laboratory features, and predictive factors in Kinshasa, the Democratic Republic of Congo
por: Wumba, Roger D, et al.
Publicado: (2015)

Pathogenesis of the inflammatory bowel disease in context of SARS-COV-2 infection
por: Dvornikova, K. A., et al.
Publicado: (2021)

Biology and Pathogenesis of SARS-CoV-2: Understandings for Therapeutic Developments against COVID-19
por: Sharma, Homa Nath, et al.
Publicado: (2021)

Distinct Molecular Mechanisms Characterizing Pathogenesis of SARS-CoV-2
por: Lee, Su Jin, et al.
Publicado: (2022)

Nadir CD4+, religion, antiretroviral therapy, incidence of type 2 diabetes mellitus, and increasing rates of obesity among black Africans with HIV disease
por: Mandina Ndona, Madone, et al.
Publicado: (2012)

Uncontrolled hypertension among patients managed in primary healthcare facilities in Kinshasa, Democratic Republic of the Congo
por: Kika, TM, et al.
Publicado: (2016)

Cell and animal models of SARS-CoV-2 pathogenesis and immunity
por: Leist, Sarah R., et al.
Publicado: (2020)

Association of maternal anemia with other risk factors in occurrence of Great obstetrical syndromes at university clinics, Kinshasa, DR Congo
por: Tandu-Umba, Barthélémy, et al.
Publicado: (2015)

Substances of abuse and their effect on SAR-CoV-2 pathogenesis
por: Antwi, Ivy, et al.
Publicado: (2023)

The multiple roles of nsp6 in the molecular pathogenesis of SARS-CoV-2
por: Bills, Cody, et al.
Publicado: (2023)

SARS-CoV-2 Infection and Liver Disease: A Review of Pathogenesis and Outcomes
por: Baldelli, Luke, et al.
Publicado: (2023)

Epidemiology, clinical, immune, and molecular profiles of microsporidiosis and cryptosporidiosis among HIV/AIDS patients
por: Wumba, Roger, et al.
Publicado: (2012)

Mechanisms of SARS-CoV-2 Transmission and Pathogenesis
por: Harrison, Andrew G., et al.
Publicado: (2020)

The pathogenesis and alternative treatment of SARS-CoV2
por: Choi, Jun-Yong, et al.
Publicado: (2020)

Epidemiology, transmission and pathogenesis of SARS-CoV-2
por: Sindhuja, Tulasi, et al.
Publicado: (2022)

Chronic kidney disease among high school students of Kinshasa
por: Bukabau, Justine B, et al.
Publicado: (2012)

Caution is needed on the effect of altitude on the pathogenesis of SAR-CoV-2 virus()
por: Burtscher, Johannes, et al.
Publicado: (2020)

Integrative Network Biology Framework Elucidates Molecular Mechanisms of SARS-CoV-2 Pathogenesis
por: Kumar, Nilesh, et al.
Publicado: (2020)

COVID-19 and its genomic variants: Molecular pathogenesis and therapeutic interventions
por: Manna, Pulak R., et al.
Publicado: (2022)

Sars Cov Replication and Pathogenesis in Human Airway Airway Epithelial Cultures
por: Sims, Amy C., et al.
Publicado: (2006)

Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis
por: Johnson, Bryan A., et al.
Publicado: (2022)

Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis
por: Johnson, Bryan A., et al.
Publicado: (2022)

The gap in contraceptive knowledge and use between the military and non-military populations of Kinshasa, DRC, 2016–2019
por: Akilimali, Pierre Z., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oerlakcp9dg4i21hv55kpcu7jt