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Structural basis of ligand binding modes of human EAAT2

In the central nervous system (CNS), excitatory amino acid transporters (EAATs) mediate the uptake of excitatory neurotransmitter glutamate and maintain its low concentrations in the synaptic cleft for avoiding neuronal cytotoxicity. Dysfunction of EAATs can lead to many psychiatric diseases. Here w...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhenglai, Chen, Huiwen, Geng, Ze, Yu, Zhuoya, Li, Hang, Dong, Yanli, Zhang, Hongwei, Huang, Zhuo, Jiang, Juquan, Zhao, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184463/ https://www.ncbi.nlm.nih.gov/pubmed/35680945 http://dx.doi.org/10.1038/s41467-022-31031-x

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