Cargando…
Robust and accurate estimation of paralog-specific copy number for duplicated genes using whole-genome sequencing
The human genome contains hundreds of low-copy repeats (LCRs) that are challenging to analyze using short-read sequencing technologies due to extensive copy number variation and ambiguity in read mapping. Copy number and sequence variants in more than 150 duplicated genes that overlap LCRs have been...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184528/ https://www.ncbi.nlm.nih.gov/pubmed/35680869 http://dx.doi.org/10.1038/s41467-022-30930-3 |