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SMYD5 catalyzes histone H3 lysine 36 trimethylation at promoters

Histone marks, carriers of epigenetic information, regulate gene expression. In mammalian cells, H3K36me3 is mainly catalyzed by SETD2 at gene body regions. Here, we find that in addition to gene body regions, H3K36me3 is enriched at promoters in primary cells. Through screening, we identify SMYD5,...

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Detalles Bibliográficos
Autores principales:	Zhang, Yanjun, Fang, Yuan, Tang, Yin, Han, Shixun, Jia, Junqi, Wan, Xinyi, Chen, Jiaqi, Yuan, Ying, Zhao, Bin, Fang, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184575/ https://www.ncbi.nlm.nih.gov/pubmed/35680905 http://dx.doi.org/10.1038/s41467-022-30940-1

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