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A statistical perspective on baseline adjustment in pharmacogenomic genome-wide association studies of quantitative change
In pharmacogenetic (PGx) studies, drug response phenotypes are often measured in the form of change in a quantitative trait before and after treatment. There is some debate in recent literature regarding baseline adjustment, or inclusion of pre-treatment or baseline value as a covariate, in PGx geno...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184591/ https://www.ncbi.nlm.nih.gov/pubmed/35680959 http://dx.doi.org/10.1038/s41525-022-00303-2 |