Three dimensional reconstruction of the mouse cerebellum in Hedgehog-driven medulloblastoma models to identify Norrin-dependent effects on preneoplasia

Spontaneous mouse models of medulloblastoma (MB) offer a tractable system to study malignant progression in the brain. Mouse Sonic Hedgehog (Shh)-MB tumours first appear at postnatal stages as preneoplastic changes on the surface of the cerebellum, the external granule layer (EGL). Here we compared...

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Detalles Bibliográficos
Autores principales: Pokrajac, Nenad T., Gurdita, Akshay, Tachibana, Nobuhiko, Tokarew, Nicholas J. A., Wallace, Valerie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184598/
https://www.ncbi.nlm.nih.gov/pubmed/35680976
http://dx.doi.org/10.1038/s42003-022-03507-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184598/
https://www.ncbi.nlm.nih.gov/pubmed/35680976
http://dx.doi.org/10.1038/s42003-022-03507-5

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