Pan-cancer analysis of genomic scar patterns caused by homologous repair deficiency (HRD)

Homologous repair deficiency (HRD) is present in many cancer types at variable prevalence and can indicate response to platinum-based chemotherapy and PARP inhibition. We developed a tumor classification system based on the loss of function of genes in the homologous recombination repair (HRR) pathw...

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Detalles Bibliográficos
Autores principales: Rempel, E., Kluck, K., Beck, S., Ourailidis, I., Kazdal, D., Neumann, O., Volckmar, A. L., Kirchner, M., Goldschmid, H., Pfarr, N., Weichert, W., Hübschmann, D., Fröhling, S., Sutter, C., Schaaf, C. P., Schirmacher, P., Endris, V., Stenzinger, A., Budczies, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184602/
https://www.ncbi.nlm.nih.gov/pubmed/35681079
http://dx.doi.org/10.1038/s41698-022-00276-6

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