Cargando…

Durable benefit and change in TCR clonality with nivolumab in a Lynch syndrome–associated glioma

Germline replication-repair deficient (gRRD) gliomas are exceptional events, and only a few of them have been treated with immune checkpoint inhibitors (ICIs). Contrary to sporadic gliomas, where ICIs have failed to show any objective benefit, the very few patients with gRRD gliomas treated with ICI...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cabezas-Camarero, Santiago, Pérez-Alfayate, Rebeca, García-Barberán, Vanesa, Polidura, María Carmen, Gómez-Ruiz, María Natividad, Casado-Fariñas, Isabel, Subhi-Issa, Issa Ahmad, Hernández, José Carlos Plaza, Garre, Pilar, Díaz-Millán, Isabel, Pérez-Segura, Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185004/ https://www.ncbi.nlm.nih.gov/pubmed/35694191 http://dx.doi.org/10.1177/17588359221100863

Ejemplares similares

Detection of IDH1 Mutations in Plasma Using BEAMing Technology in Patients with Gliomas
por: Cabezas-Camarero, Santiago, et al.
Publicado: (2022)

Lung Adenocarcinoma with Lynch Syndrome and the Response to Nivolumab
por: Kawashima, Yosuke, et al.
Publicado: (2019)

Glioblastoma: an organ-confined disease?
por: Cabezas-Camarero, Santiago, et al.
Publicado: (2022)

Quantification of HTLV-1 Clonality and TCR Diversity
por: Laydon, Daniel J., et al.
Publicado: (2014)

Pitfalls in TCR gene clonality testing: teaching cases
por: Groenen, Patricia J. T. A., et al.
Publicado: (2008)

Predominant Role of T Cell Receptor (TCR)-α Chain in Forming Preimmune TCR Repertoire Revealed by Clonal TCR Reconstitution System
por: Yokosuka, Tadashi, et al.
Publicado: (2002)

EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferations
por: Langerak, A W, et al.
Publicado: (2012)

Frequency and Variability of Genomic Rearrangements on MSH2 in Spanish Lynch Syndrome Families
por: Romero, Atocha, et al.
Publicado: (2013)

Nivolumab to pembrolizumab switch induced a durable melanoma response: A case report
por: Lepir, Tanja, et al.
Publicado: (2019)

Durable Expansion of TCR-δ Meta-Clonotypes After BCG Revaccination in Humans
por: James, Charlotte A., et al.
Publicado: (2022)

Idiopathic stenosis of foramina of Monro in an asymptomatic adult patient: a rare entity radiologists should be aware of
por: Gomez-Ruiz, Natividad, et al.
Publicado: (2020)

Diagnostic significance of TCR gene clonal rearrangement analysis in early mycosis fungoides
por: Xu, Chen, et al.
Publicado: (2011)

Evaluation of the TCR Repertoire as a Predictive and Prognostic Biomarker in Cancer: Diversity or Clonality?
por: Aran, Andrea, et al.
Publicado: (2022)

Durable response to nivolumab in a lung adenocarcinoma patient with idiopathic pulmonary fibrosis
por: Ide, Maako, et al.
Publicado: (2018)

A Durable Response after the Discontinuation of Nivolumab in an Advanced Gastric Cancer Patient
por: Yatsuda, Yukino, et al.
Publicado: (2020)

TCR-dependent differentiation of thymic Foxp3(+) cells is limited to small clonal sizes
por: Leung, Monica W.L., et al.
Publicado: (2009)

Decreased cytotoxic T cells and TCR clonality in organ transplant recipients with squamous cell carcinoma
por: Frazzette, Nicholas, et al.
Publicado: (2020)

Prevalence of Lynch Syndrome among Patients with Newly Diagnosed Endometrial Cancers
por: Egoavil, Cecilia, et al.
Publicado: (2013)

TCR Clonality and Genomic Instability Signatures as Prognostic Biomarkers in High Grade Serous Ovarian Cancer
por: Lecuelle, Julie, et al.
Publicado: (2021)

T-lymphoblastic lymphoma/leukemia without clonal TCR gene rearrangements: case report and literature review
por: Wang, Jiuju, et al.
Publicado: (2021)

Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality
por: Shi, Tiffany, et al.
Publicado: (2023)

“Brain Fog” by COVID-19 or Alzheimer’s Disease? A Case Report
por: Matias-Guiu, Jordi A., et al.
Publicado: (2021)

Charles Lynch and His Vestigial Legacy—Workplace Lynching
por: Ramasubban, Suresh
Publicado: (2019)

An Insight into the lynch Syndrome: Retrospective Study of the Pattern of Presentation and Management of Lynch Syndrome in Pakistan
por: Khan, Faraz Faisal, et al.
Publicado: (2023)

Liquid Biopsy in Head and Neck Cancer: Current Evidence and Future Perspective on Squamous Cell, Salivary Gland, Paranasal Sinus and Nasopharyngeal Cancers
por: Cabezas-Camarero, Santiago, et al.
Publicado: (2022)

RNA-Seq-Based TCR Profiling Reveals Persistently Increased Intratumoral Clonality in Responders to Anti-PD-1 Therapy
por: Zhigalova, Ekaterina A., et al.
Publicado: (2020)

Relative quantification of TCR Vbeta-chain families by real time PCR for identification of clonal T-cell populations
por: Ochsenreither, Sebastian, et al.
Publicado: (2008)

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection
por: Nunes-Alves, Cláudio, et al.
Publicado: (2015)

MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A
por: Howson, Lauren J., et al.
Publicado: (2018)

Clonal Distribution and Intratumor Heterogeneity of the TCR Repertoire in Papillary Thyroid Cancer With or Without Coexistent Hashimoto’s Thyroiditis
por: Cui, Likun, et al.
Publicado: (2022)

The Statesboro Lynching
Publicado: (1904)

Clinical Behavior, Mutational Profile and T-Cell Repertoire of High-Grade Neuroendocrine Tumors of the Head and Neck
por: Cabezas-Camarero, Santiago, et al.
Publicado: (2023)

Application and challenges of TCR and BCR sequencing to investigate T- and B-cell clonality in elastase-induced experimental murine abdominal aortic aneurysm
por: Elster, Christin, et al.
Publicado: (2023)

The Feature of Distribution and Clonality of TCR γ/δ Subfamilies T Cells in Patients with B-Cell Non-Hodgkin Lymphoma
por: Wang, Liang, et al.
Publicado: (2014)

Correction: Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection
Publicado: (2015)

LRT: Integrative analysis of scRNA-seq and scTCR-seq data to investigate clonal differentiation heterogeneity
por: Xie, Juan, et al.
Publicado: (2023)

TCR repertoire profiling revealed antigen-driven CD8+ T cell clonal groups shared in synovial fluid of patients with spondyloarthritis
por: Komech, Ekaterina A., et al.
Publicado: (2022)

Durable tumor regression in highly refractory metastatic KIT/PDGFRA wild-type GIST following treatment with nivolumab
por: Schroeder, Brett A., et al.
Publicado: (2020)

Complete and Durable Response to Nivolumab in Recurrent Poorly Differentiated Pancreatic Neuroendocrine Carcinoma with High Tumor Mutational Burden
por: Kang, Nai-Wen, et al.
Publicado: (2021)

Transcriptomic Correlates of Immunologic Activation in Head and Neck and Cervical Cancer
por: Saiz-Ladera, Cristina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2oc26in0dfj3tv7t3ehsdp2bvl