Cargando…

BPTF activates the MAPK pathway through coexpression with Raf1 to promote proliferation of T-cell lymphoma

The aim of the present study was to explore the role and biological function of bromodomain PHD finger transcription factor (BPTF) in T-cell lymphoma. Reverse transcription-quantitative PCR (RT-qPCR), western blotting, immunohistochemistry and bioinformatics analysis were used to determine the expre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bai, Dongyu, Zhou, Yong, Shen, Fayan, Gao, Dehong, Suo, Wenhao, Zhang, Haiping, Li, Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185150/ https://www.ncbi.nlm.nih.gov/pubmed/35720479 http://dx.doi.org/10.3892/ol.2022.13344

Ejemplares similares

BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas
por: Dai, Meng, et al.
Publicado: (2015)

PHF6 recruits BPTF to promote HIF-dependent pathway and progression in YAP-high breast cancer
por: Gao, Sheng, et al.
Publicado: (2023)

BPTF promotes the progression of distinct subtypes of breast cancer and is a therapeutic target
por: Bezrookove, Vladimir, et al.
Publicado: (2022)

TRIM22 promotes the proliferation of glioblastoma cells by activating MAPK signaling and accelerating the degradation of Raf-1
por: Fei, Xiaowei, et al.
Publicado: (2023)

Registered report: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
por: Bhargava, Ajay, et al.
Publicado: (2016)

BPTF Regulates Growth of Adult and Pediatric High-Grade Glioma through the MYC Pathway
por: Green, Adam L., et al.
Publicado: (2019)

The Role of BPTF in Melanoma Progression and in Response to BRAF-Targeted Therapy
por: Dar, Altaf A., et al.
Publicado: (2015)

BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis
por: Richart, Laia, et al.
Publicado: (2016)

YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathways
por: Ou, Wen-Bin, et al.
Publicado: (2021)

Melatonin promotes Schwann cell dedifferentiation and proliferation through the Ras/Raf/ERK and MAPK pathways, and glial cell-derived neurotrophic factor expression
por: Tiong, Yee Lian, et al.
Publicado: (2020)

circ-BPTF serves as a miR-486-5p sponge to regulate CEMIP and promotes hypoxic pulmonary arterial smooth muscle cell proliferation in COPD: Hpoxia induces circ-BPTF/miR-486-5p/CEMIP axis in COPD
por: Wang, Changguo, et al.
Publicado: (2022)

BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits
por: Zhao, Xinrui, et al.
Publicado: (2018)

RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition
por: Jin, Ting, et al.
Publicado: (2017)

BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells
por: Frey, Wesley D., et al.
Publicado: (2017)

The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome
por: Morrison, Emma A, et al.
Publicado: (2018)

BPTF inhibits NK cell activity and the abundance of natural cytotoxicity receptor co-ligands
por: Mayes, Kimberly, et al.
Publicado: (2017)

Phenotypic expansion of the BPTF‐related neurodevelopmental disorder with dysmorphic facies and distal limb anomalies
por: Glinton, Kevin E., et al.
Publicado: (2021)

BPTF inhibition antagonizes colorectal cancer progression by transcriptionally inactivating Cdc25A
por: Guo, Ping, et al.
Publicado: (2022)

Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway
por: Sun, Jian, et al.
Publicado: (2020)

Essential Role of Chromatin Remodeling Protein Bptf in Early Mouse Embryos and Embryonic Stem Cells
por: Landry, Joseph, et al.
Publicado: (2008)

A Novel Translocation Breakpoint within the BPTF Gene Is Associated with a Pre-Malignant Phenotype
por: Buganim, Yosef, et al.
Publicado: (2010)

Black Rice Anthocyanins Suppress Metastasis of Breast Cancer Cells by Targeting RAS/RAF/MAPK Pathway
por: Chen, Xiang-Yan, et al.
Publicado: (2015)

Wedelolactone Attenuates Pulmonary Fibrosis Partly Through Activating AMPK and Regulating Raf-MAPKs Signaling Pathway
por: Yang, Jin-yu, et al.
Publicado: (2019)

Circ-BPTF promotes bladder cancer progression and recurrence through the miR-31-5p/RAB27A axis
por: Bi, Junming, et al.
Publicado: (2018)

“RAF” neighborhood: Protein–protein interaction in the Raf/Mek/Erk pathway
por: Cseh, Botond, et al.
Publicado: (2014)

Targeting regulation of VEGF by BPTF in non-small cell lung cancer and its potential clinical significance
por: Dai, Meng, et al.
Publicado: (2022)

The Pathway Coexpression Network: Revealing pathway relationships
por: Pita-Juárez, Yered, et al.
Publicado: (2018)

Mutant K-ras oncogene regulates steroidogenesis of normal human adrenocortical cells by the RAF-MEK-MAPK pathway
por: Wu, C-H, et al.
Publicado: (2002)

Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa
por: Jafari, Meryem, et al.
Publicado: (2022)

Correction for: Circ‐BPTF promotes bladder cancer progression and recurrence through the miR‐31‐5p/RAB27A axis
por: Bi, Junming, et al.
Publicado: (2021)

Strong negative feedback from Erk to Raf confers robustness to MAPK signalling
por: Fritsche-Guenther, Raphaela, et al.
Publicado: (2011)

Suppression of B-Raf(V600E) cancers by MAPK hyper-activation
por: Atiq, Rawan, et al.
Publicado: (2016)

BPTF in bone marrow provides a potential progression biomarker regulated by TFAP4 through the PI3K/AKT pathway in neuroblastoma
por: Jiang, Chiyi, et al.
Publicado: (2023)

Monocyte Chemoattractant Protein-1 promotes cancer cell migration via c-Raf/MAPK/AP-1 pathway and MMP-9 production in osteosarcoma
por: Liu, Ju-Fang, et al.
Publicado: (2020)

Targeting BPTF Sensitizes Pancreatic Ductal Adenocarcinoma to Chemotherapy by Repressing ABC-Transporters and Impairing Multidrug Resistance (MDR)
por: Muñoz Velasco, Raúl, et al.
Publicado: (2022)

Harmine suppresses hyper-activated Ras–MAPK pathway by selectively targeting oncogenic mutated Ras/Raf in Caenorhabditis elegans
por: Ji, Jiaojiao, et al.
Publicado: (2019)

Clinical Significance of Somatic Mutations in RAS/RAF/MAPK Signaling Pathway in Moroccan and North African Colorectal Cancer Patients
por: Benmokhtar, Soukaina, et al.
Publicado: (2022)

Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma
por: Zhang, Chuanjie, et al.
Publicado: (2021)

MiR-155-5p suppresses SOX1 to promote proliferation of cholangiocarcinoma via RAF/MEK/ERK pathway
por: Wang, Da, et al.
Publicado: (2021)

Up-regulation of microRNA-497 inhibits the proliferation, migration and invasion but increases the apoptosis of multiple myeloma cells through the MAPK/ERK signaling pathway by targeting Raf-1
por: Ye, Cheng-Yu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_p9bbr0mbsvgtufa4fafpah94rh