Significant accumulation of KRAS mutations in bronchiolar metaplasia-associated honeycomb lesions of interstitial pneumonia

Interstitial pneumonia (IP) is a major risk factor for lung adenocarcinoma (LADC). IP-related LADC predominantly develops in the bronchiolar metaplasia lining in honeycomb lesions. Kirsten rat sarcoma virus (KRAS) is the most common oncogene mutated in IP-related LADC. The present study examined the...

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Detalles Bibliográficos
Autores principales: Kataoka, Toshiaki, Okudela, Koji, Matsumura, Mai, Baba, Tomohisa, Kitamura, Hideya, Arai, Hiromasa, Suzuki, Takeshisa, Koike, Chihiro, Mutsui, Hideaki, Sekiya, Motoki, Sugiyama, Misaki, Takemura, Tamiko, Iwasawa, Tae, Ogura, Takashi, Ohashi, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185152/
https://www.ncbi.nlm.nih.gov/pubmed/35720499
http://dx.doi.org/10.3892/ol.2022.13346

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