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Astrocytic function is associated with both amyloid-β and tau pathology in non-demented APOE ϵ4 carriers

A growing body of evidence suggests that astrocytes play a major role in the pathophysiology of Alzheimer’s disease. Given that APOE is primarily expressed in astrocytes, these cells might be an important link between the APOE ε4 allele and the development of Alzheimer’s disease pathology. Here, we...

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Detalles Bibliográficos
Autores principales:	Spotorno, Nicola, Najac, Chloé, Stomrud, Erik, Mattsson-Carlgren, Niklas, Palmqvist, Sebastian, van Westen, Danielle, Ronen, Itamar, Hansson, Oskar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185373/ https://www.ncbi.nlm.nih.gov/pubmed/35702728 http://dx.doi.org/10.1093/braincomms/fcac135

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