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Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease

Sleep disorders are one of the most common non-motor symptoms in Parkinson's disease (PD). It can cause a notable decrease in quality of life and functioning in PD patients, as well as place a huge burden on both patients and caregivers. The most cited sleep disorders in PD included insomnia, r...

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Autores principales: Taximaimaiti, Reyisha, Luo, Xingguang, Wang, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185775/
https://www.ncbi.nlm.nih.gov/pubmed/33998990
http://dx.doi.org/10.2174/1570159X19666210517115706
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author Taximaimaiti, Reyisha
Luo, Xingguang
Wang, Xiao-Ping
author_facet Taximaimaiti, Reyisha
Luo, Xingguang
Wang, Xiao-Ping
author_sort Taximaimaiti, Reyisha
collection PubMed
description Sleep disorders are one of the most common non-motor symptoms in Parkinson's disease (PD). It can cause a notable decrease in quality of life and functioning in PD patients, as well as place a huge burden on both patients and caregivers. The most cited sleep disorders in PD included insomnia, restless legs syndrome (RLS), rapid eye movement (REM), sleep behavior disorders (RBD), excessive daytime sleepiness (EDS) and sleep disordered breathing (SDB), which can appear alone or several at the same time. In this review, we listed the recommended pharmacological treatments for common sleep disorders in PD, and discussed the recommended dosages, benefits and side effects of relative drugs. We also discussed non-pharmacological treatments to improve sleep quality, including sleep hygiene education, exercise, deep brain stimulation, cognitive behavior therapy and complementary therapies. We tried to find proper interventions for different types of sleep disorders in PD, while minimizing relative side effects.
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spelling pubmed-91857752022-06-28 Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease Taximaimaiti, Reyisha Luo, Xingguang Wang, Xiao-Ping Curr Neuropharmacol Article Sleep disorders are one of the most common non-motor symptoms in Parkinson's disease (PD). It can cause a notable decrease in quality of life and functioning in PD patients, as well as place a huge burden on both patients and caregivers. The most cited sleep disorders in PD included insomnia, restless legs syndrome (RLS), rapid eye movement (REM), sleep behavior disorders (RBD), excessive daytime sleepiness (EDS) and sleep disordered breathing (SDB), which can appear alone or several at the same time. In this review, we listed the recommended pharmacological treatments for common sleep disorders in PD, and discussed the recommended dosages, benefits and side effects of relative drugs. We also discussed non-pharmacological treatments to improve sleep quality, including sleep hygiene education, exercise, deep brain stimulation, cognitive behavior therapy and complementary therapies. We tried to find proper interventions for different types of sleep disorders in PD, while minimizing relative side effects. Bentham Science Publishers 2021-12-13 2021-12-13 /pmc/articles/PMC9185775/ /pubmed/33998990 http://dx.doi.org/10.2174/1570159X19666210517115706 Text en © 2021 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Taximaimaiti, Reyisha
Luo, Xingguang
Wang, Xiao-Ping
Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease
title Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease
title_full Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease
title_fullStr Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease
title_full_unstemmed Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease
title_short Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease
title_sort pharmacological and non-pharmacological treatments of sleep disorders in parkinson's disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185775/
https://www.ncbi.nlm.nih.gov/pubmed/33998990
http://dx.doi.org/10.2174/1570159X19666210517115706
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