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Genomic temporal heterogeneity of circulating tumour DNA in unresectable metastatic colorectal cancer under first-line treatment

OBJECTIVE: Circulating tumour DNA (ctDNA) sequencing is increasingly used in the clinical management of patients with colorectal cancer. However, the genomic heterogeneity in ctDNA during treatments and its impact on clinical outcomes remain largely unknown. DESIGN: We conducted a prospective cohort...

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Detalles Bibliográficos
Autores principales:	Wang, Feng, Huang, You-Sheng, Wu, Hao-Xiang, Wang, Zi-Xian, Jin, Ying, Yao, Yi-Chen, Chen, Yan-Xing, Zhao, Qi, Chen, Shifu, He, Ming-Ming, Luo, Hui-Yan, Qiu, Miao-Zhen, Wang, De-shen, Wang, Feng-Hua, Xu, Mingyan, Li, Yu-Hong, Xu, Rui-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Colon
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185813/ https://www.ncbi.nlm.nih.gov/pubmed/34489309 http://dx.doi.org/10.1136/gutjnl-2021-324852

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