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Early-Stage Loss of GALNT6 Predicts Poor Clinical Outcome in Colorectal Cancer

Colorectal adenocarcinomas arise from luminal lining epithelium of the colorectal tract which is covered with highly glycosylated mucins. Mucin O-glycosylation is initiated by a family of polypeptide N-acteylgalactosaminyltransferases (GALNTs). This study examined GALNT6 protein expression in 679 co...

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Detalles Bibliográficos
Autores principales: Ogawa, Makiko, Tanaka, Atsushi, Namba, Kei, Shia, Jinru, Wang, Julia Y., Roehrl, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185839/
https://www.ncbi.nlm.nih.gov/pubmed/35692787
http://dx.doi.org/10.3389/fonc.2022.802548