Characterization of stem cell landscape and identification of stemness-relevant prognostic gene signature to aid immunotherapy in colorectal cancer

BACKGROUND: It is generally accepted that colorectal cancer (CRC) originates from cancer stem cells (CSCs), which are responsible for CRC progression, metastasis and therapy resistance. The high heterogeneity of CSCs has precluded clinical application of CSC-targeting therapy. Here, we aimed to char...

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Detalles Bibliográficos
Autores principales: Zheng, Hang, Liu, Heshu, Li, Huayu, Dou, Weidong, Wang, Jingui, Zhang, Junling, Liu, Tao, Wu, Yingchao, Liu, Yucun, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185878/
https://www.ncbi.nlm.nih.gov/pubmed/35681225
http://dx.doi.org/10.1186/s13287-022-02913-0

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