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CONET: copy number event tree model of evolutionary tumor history for single-cell data

Copy number alterations constitute important phenomena in tumor evolution. Whole genome single-cell sequencing gives insight into copy number profiles of individual cells, but is highly noisy. Here, we propose CONET, a probabilistic model for joint inference of the evolutionary tree on copy number e...

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Detalles Bibliográficos
Autores principales:	Markowska, Magda, Cąkała, Tomasz, Miasojedow, BłaŻej, Aybey, Bogac, Juraeva, Dilafruz, Mazur, Johanna, Ross, Edith, Staub, Eike, Szczurek, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185904/ https://www.ncbi.nlm.nih.gov/pubmed/35681161 http://dx.doi.org/10.1186/s13059-022-02693-z

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