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Tissue catabolism and donor-specific dexamethasone response in a human osteochondral model of post-traumatic osteoarthritis

BACKGROUND: Post-traumatic osteoarthritis (PTOA) does not currently have clinical prognostic biomarkers or disease-modifying drugs, though promising candidates such as dexamethasone (Dex) exist. Many challenges in studying and treating this disease stem from tissue interactions that complicate under...

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Detalles Bibliográficos
Autores principales:	Black, Rebecca Mae, Flaman, Lisa L., Lindblom, Karin, Chubinskaya, Susan, Grodzinsky, Alan J., Önnerfjord, Patrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185927/ https://www.ncbi.nlm.nih.gov/pubmed/35689293 http://dx.doi.org/10.1186/s13075-022-02828-4

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