Chlorogenic acid exerts neuroprotective effect against hypoxia-ischemia brain injury in neonatal rats by activating Sirt1 to regulate the Nrf2-NF-κB signaling pathway

BACKGROUND: Neonatal hypoxic-ischemic brain injury (HIE) is caused by perinatal asphyxia, which is associated with various confounding factors. Although studies on the pathogenesis and treatment of HIE have matured, sub-hypothermia is the only clinical treatment available for HIE. Previous evidence...

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Detalles Bibliográficos
Autores principales: Zheng, Yihui, Li, Luyao, Chen, Binwen, Fang, Yu, Lin, Wei, Zhang, Tianlei, Feng, Xiaoli, Tao, Xiaoyue, Wu, Yiqing, Fu, Xiaoqin, Lin, Zhenlang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185968/
https://www.ncbi.nlm.nih.gov/pubmed/35689269
http://dx.doi.org/10.1186/s12964-022-00860-0

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