Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell phenotype

Adult salivary stem/progenitor cells (SSPC) have an intrinsic property to self-renew in order to maintain tissue architecture and homeostasis. Adult salivary glands have been documented to harbor SSPC, which have been shown to play a vital role in the regeneration of the glandular structures postrad...

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Detalles Bibliográficos
Autores principales: Viswanathan, Vignesh, Cao, Hongbin, Saiki, Julie, Jiang, Dadi, Mattingly, Aaron, Nambiar, Dhanya, Bloomstein, Joshua, Li, Yang, Jiang, Sizun, Chamoli, Manish, Sirjani, Davud, Kaplan, Michael, Holsinger, F Christopher, Liang, Rachel, Von Eyben, Rie, Jiang, Haowen, Guan, Li, Lagory, Edward, Feng, Zhiping, Nolan, Garry, Ye, Jiangbin, Denko, Nicholas, Knox, Sarah, Rosen, Daria-Mochly, Le, Quynh-Thu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186046/
https://www.ncbi.nlm.nih.gov/pubmed/35707206
http://dx.doi.org/10.1093/pnasnexus/pgac056

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