Cross-species metabolomic analysis of tau- and DDT-related toxicity

Exposure to the pesticide dichlorodiphenyltrichloroethane (DDT) has been associated with increased risk of Alzheimer's disease (AD), a disease also associated with hyperphosphorylated tau (p-tau) protein aggregation. We investigated whether exposure to DDT can exacerbate tau protein toxicity in...

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Detalles Bibliográficos
Autores principales: Kalia, Vrinda, Niedzwiecki, Megan M, Bradner, Joshua M, Lau, Fion K, Anderson, Faith L, Bucher, Meghan L, Manz, Katherine E, Schlotter, Alexa Puri, Fuentes, Zoe Coates, Pennell, Kurt D, Picard, Martin, Walker, Douglas I, Hu, William T, Jones, Dean P, Miller, Gary W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186048/
https://www.ncbi.nlm.nih.gov/pubmed/35707205
http://dx.doi.org/10.1093/pnasnexus/pgac050

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