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From Insect Bites to a Skin Autoimmune Disease: A Conceivable Pathway to Endemic Pemphigus Foliaceus

In the endemic variants of pemphigus foliaceus (PF), in Brazil and Tunisia, patients generate pathogenic IgG4 anti-desmoglein 1 autoantibodies. Additionally, these patients possess antibodies against salivary proteins from sand flies that react with Dsg1, which may lead to skin disease in susceptibl...

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Detalles Bibliográficos
Autores principales: Li, Ning, Aoki, Valeria, Liu, Zhi, Prisayanh, Phillip, Valenzuela, Jesus G., Diaz, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186141/
https://www.ncbi.nlm.nih.gov/pubmed/35693761
http://dx.doi.org/10.3389/fimmu.2022.907424