Elevated expression of miR-494-3p is associated with resistance to osimertinib in EGFR T790M-positive non-small cell lung cancer

BACKGROUND: Non-small cell lung cancer (NSCLC) harboring activating mutations in the gene encoding epidermal growth factor receptor (EGFR) is amenable for targeted therapy with tyrosine kinase inhibitors (TKIs). Eventually, resistance to TKI-therapy occurs resulting in disease progression. A substan...

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Detalles Bibliográficos
Autores principales: Kaźmierczak, Dominika, Eide, Inger Johanne Zwicky, Gencheva, Radosveta, Lai, Yi, Lewensohn, Rolf, Tsakonas, Georgios, Grundberg, Oscar, de Petris, Luigi, McGowan, Marc, Brustugun, Odd Terje, Ekman, Simon, Hydbring, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186160/
https://www.ncbi.nlm.nih.gov/pubmed/35693293
http://dx.doi.org/10.21037/tlcr-21-955

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