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Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistance

BACKGROUND: Tyrosine kinase inhibitor (TKI) treatment has significantly improved the prognosis of oncogenic-driven lung adenocarcinoma (LUAD). However, drug resistance limits the long-term benefits of patients. Therefore, there is a pressing need to explore the mechanism of TKI resistance and identi...

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Detalles Bibliográficos
Autores principales:	Zhang, Chuanfen, Wang, Chunmei, Yang, Zhenyu, Bai, Yuquan, Shukuya, Takehito, Poh, Mau-Ern, Ekman, Simon, Li, Jian, Xu, Yuyang, Deng, Senyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186177/ https://www.ncbi.nlm.nih.gov/pubmed/35693278 http://dx.doi.org/10.21037/tlcr-22-318

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