ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL-8/Notch signaling cascade

ALDH1A1 is a cytosolic enzyme upregulated in tumor cells, involved in detoxifying cells from reactive aldehydes and in acquiring resistance to chemotherapeutic drugs. Its expression correlates with poor clinical outcomes in a number of cancers, including melanoma. The present study hypothesized that...

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Detalles Bibliográficos
Autores principales: Ciccone, Valerio, Terzuoli, Erika, Ristori, Emma, Filippelli, Arianna, Ziche, Marina, Morbidelli, Lucia, Donnini, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186295/
https://www.ncbi.nlm.nih.gov/pubmed/35656893
http://dx.doi.org/10.3892/ijmm.2022.5155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186295/
https://www.ncbi.nlm.nih.gov/pubmed/35656893
http://dx.doi.org/10.3892/ijmm.2022.5155

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