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ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL-8/Notch signaling cascade

ALDH1A1 is a cytosolic enzyme upregulated in tumor cells, involved in detoxifying cells from reactive aldehydes and in acquiring resistance to chemotherapeutic drugs. Its expression correlates with poor clinical outcomes in a number of cancers, including melanoma. The present study hypothesized that...

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Detalles Bibliográficos
Autores principales:	Ciccone, Valerio, Terzuoli, Erika, Ristori, Emma, Filippelli, Arianna, Ziche, Marina, Morbidelli, Lucia, Donnini, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186295/ https://www.ncbi.nlm.nih.gov/pubmed/35656893 http://dx.doi.org/10.3892/ijmm.2022.5155

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