Orally delivered rutin in lipid-based nano-formulation exerts strong antithrombotic effects by protein disulfide isomerase inhibition

Thrombosis occurs in both macrovasculature and microvasculature, causing various cardio-cerebral vascular diseases. The lack of effective and safe antithrombotic drugs leads to a public health crisis. Mounting evidence suggests that protein disulfide isomerase (PDI) plays a critical role in the init...

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Detalles Bibliográficos
Autores principales: Chen, Dan, Liu, Yurong, Liu, Peiwen, Zhou, Yang, Jiang, Longguang, Yuan, Cai, Huang, Mingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186361/
https://www.ncbi.nlm.nih.gov/pubmed/35674505
http://dx.doi.org/10.1080/10717544.2022.2083726

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