Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance

Senescence is a stress-responsive tumor suppressor mechanism associated with expression of the senescence-associated secretory phenotype (SASP). Through the SASP, senescent cells trigger their own immune-mediated elimination, which if evaded leads to tumorigenesis. Senescent parenchymal cells are se...

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Detalles Bibliográficos
Autores principales: Yin, Kelvin, Patten, Daniel, Gough, Sarah, de Barros Gonçalves, Susana, Chan, Adelyne, Olan, Ioana, Cassidy, Liam, Poblocka, Marta, Zhu, Haoran, Lun, Aaron, Schuijs, Martijn, Young, Andrew, Martinez-Jimenez, Celia, Halim, Timotheus Y.F., Shetty, Shishir, Narita, Masashi, Hoare, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186388/
https://www.ncbi.nlm.nih.gov/pubmed/35618311
http://dx.doi.org/10.1101/gad.349585.122

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