Protocol for a Phase 1, Open-Label, Multiple-Center, Dose-Escalation Study to Evaluate the Safety and Tolerability of ADR-001 in the Treatment of Immunoglobulin A Nephropathy

INTRODUCTION: Immunoglobulin A (IgA) nephropathy is a disease that presents with urinary symptoms such as glomerular hematuria and urinary protein positivity, with predominant deposition of IgA in the mesangial region of the glomerulus. Corticosteroids are mainly used for treatment; however, infecti...

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Detalles Bibliográficos
Autores principales: Tanaka, Akihito, Furuhashi, Kazuhiro, Fujieda, Kumiko, Maeda, Kayaho, Saito, Shoji, Mimura, Tetsushi, Saka, Yosuke, Naruse, Tomohiko, Ishimoto, Takuji, Kosugi, Tomoki, Kinoshita, Fumie, Kuwatsuka, Yachiyo, Shimizu, Shinobu, Nakai, Yasuhiro, Maruyama, Shoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186503/
https://www.ncbi.nlm.nih.gov/pubmed/35692547
http://dx.doi.org/10.3389/fmed.2022.883168

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