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On the management of population immunity()
This paper considers a susceptible-infected-recovered type model of infectious diseases, such as COVID-19 or swine flu, in which costly treatment or vaccination confers immunity on recovered individuals. Once immune, individuals indirectly protect the remaining susceptibles, who benefit from a measu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186754/ https://www.ncbi.nlm.nih.gov/pubmed/35702334 http://dx.doi.org/10.1016/j.jet.2022.105501 |
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author | Toxvaerd, Flavio Rowthorn, Robert |
author_facet | Toxvaerd, Flavio Rowthorn, Robert |
author_sort | Toxvaerd, Flavio |
collection | PubMed |
description | This paper considers a susceptible-infected-recovered type model of infectious diseases, such as COVID-19 or swine flu, in which costly treatment or vaccination confers immunity on recovered individuals. Once immune, individuals indirectly protect the remaining susceptibles, who benefit from a measure of herd immunity. Treatment and vaccination directly induce such herd immunity, which builds up over time. Optimal treatment is shown to involve intervention at early stages of the epidemic, while optimal vaccination may defer intervention to intermediate stages. Thus, while treatment and vaccination have superficial similarities, their effects and desirability at different stages of the epidemic are different. Equilibrium vaccination is qualitatively similar to socially optimal vaccination, while equilibrium treatment differs in nature from socially optimal treatment. The optimal policies are compared to traditional non-economic public health interventions which rely on herd immunity thresholds. |
format | Online Article Text |
id | pubmed-9186754 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91867542022-06-10 On the management of population immunity() Toxvaerd, Flavio Rowthorn, Robert J Econ Theory Article This paper considers a susceptible-infected-recovered type model of infectious diseases, such as COVID-19 or swine flu, in which costly treatment or vaccination confers immunity on recovered individuals. Once immune, individuals indirectly protect the remaining susceptibles, who benefit from a measure of herd immunity. Treatment and vaccination directly induce such herd immunity, which builds up over time. Optimal treatment is shown to involve intervention at early stages of the epidemic, while optimal vaccination may defer intervention to intermediate stages. Thus, while treatment and vaccination have superficial similarities, their effects and desirability at different stages of the epidemic are different. Equilibrium vaccination is qualitatively similar to socially optimal vaccination, while equilibrium treatment differs in nature from socially optimal treatment. The optimal policies are compared to traditional non-economic public health interventions which rely on herd immunity thresholds. Elsevier Inc. 2022-09 2022-06-10 /pmc/articles/PMC9186754/ /pubmed/35702334 http://dx.doi.org/10.1016/j.jet.2022.105501 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Toxvaerd, Flavio Rowthorn, Robert On the management of population immunity() |
title | On the management of population immunity() |
title_full | On the management of population immunity() |
title_fullStr | On the management of population immunity() |
title_full_unstemmed | On the management of population immunity() |
title_short | On the management of population immunity() |
title_sort | on the management of population immunity() |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186754/ https://www.ncbi.nlm.nih.gov/pubmed/35702334 http://dx.doi.org/10.1016/j.jet.2022.105501 |
work_keys_str_mv | AT toxvaerdflavio onthemanagementofpopulationimmunity AT rowthornrobert onthemanagementofpopulationimmunity |