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On the management of population immunity()

This paper considers a susceptible-infected-recovered type model of infectious diseases, such as COVID-19 or swine flu, in which costly treatment or vaccination confers immunity on recovered individuals. Once immune, individuals indirectly protect the remaining susceptibles, who benefit from a measu...

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Detalles Bibliográficos
Autores principales: Toxvaerd, Flavio, Rowthorn, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186754/
https://www.ncbi.nlm.nih.gov/pubmed/35702334
http://dx.doi.org/10.1016/j.jet.2022.105501
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author Toxvaerd, Flavio
Rowthorn, Robert
author_facet Toxvaerd, Flavio
Rowthorn, Robert
author_sort Toxvaerd, Flavio
collection PubMed
description This paper considers a susceptible-infected-recovered type model of infectious diseases, such as COVID-19 or swine flu, in which costly treatment or vaccination confers immunity on recovered individuals. Once immune, individuals indirectly protect the remaining susceptibles, who benefit from a measure of herd immunity. Treatment and vaccination directly induce such herd immunity, which builds up over time. Optimal treatment is shown to involve intervention at early stages of the epidemic, while optimal vaccination may defer intervention to intermediate stages. Thus, while treatment and vaccination have superficial similarities, their effects and desirability at different stages of the epidemic are different. Equilibrium vaccination is qualitatively similar to socially optimal vaccination, while equilibrium treatment differs in nature from socially optimal treatment. The optimal policies are compared to traditional non-economic public health interventions which rely on herd immunity thresholds.
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spelling pubmed-91867542022-06-10 On the management of population immunity() Toxvaerd, Flavio Rowthorn, Robert J Econ Theory Article This paper considers a susceptible-infected-recovered type model of infectious diseases, such as COVID-19 or swine flu, in which costly treatment or vaccination confers immunity on recovered individuals. Once immune, individuals indirectly protect the remaining susceptibles, who benefit from a measure of herd immunity. Treatment and vaccination directly induce such herd immunity, which builds up over time. Optimal treatment is shown to involve intervention at early stages of the epidemic, while optimal vaccination may defer intervention to intermediate stages. Thus, while treatment and vaccination have superficial similarities, their effects and desirability at different stages of the epidemic are different. Equilibrium vaccination is qualitatively similar to socially optimal vaccination, while equilibrium treatment differs in nature from socially optimal treatment. The optimal policies are compared to traditional non-economic public health interventions which rely on herd immunity thresholds. Elsevier Inc. 2022-09 2022-06-10 /pmc/articles/PMC9186754/ /pubmed/35702334 http://dx.doi.org/10.1016/j.jet.2022.105501 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Toxvaerd, Flavio
Rowthorn, Robert
On the management of population immunity()
title On the management of population immunity()
title_full On the management of population immunity()
title_fullStr On the management of population immunity()
title_full_unstemmed On the management of population immunity()
title_short On the management of population immunity()
title_sort on the management of population immunity()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186754/
https://www.ncbi.nlm.nih.gov/pubmed/35702334
http://dx.doi.org/10.1016/j.jet.2022.105501
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