Aryl hydrocarbon receptor blocks aging-induced senescence in the liver and fibroblast cells

Aging impairs organismal homeostasis leading to multiple pathologies. Yet, the mechanisms and molecular intermediates involved are largely unknown. Here, we report that aged aryl hydrocarbon receptor-null mice (AhR−/−) had exacerbated cellular senescence and more liver progenitor cells. Senescence-a...

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Detalles Bibliográficos
Autores principales: Nacarino-Palma, Ana, Rico-Leo, Eva M., Campisi, Judith, Ramanathan, Arvind, González-Rico, Francisco J., Rejano-Gordillo, Claudia M., Ordiales-Talavero, Ana, Merino, Jaime M., Fernández-Salguero, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186759/
https://www.ncbi.nlm.nih.gov/pubmed/35619220
http://dx.doi.org/10.18632/aging.204103

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