Safety and immunogenicity of heterologous boost immunization with an adenovirus type-5-vectored and protein-subunit-based COVID-19 vaccine (Convidecia/ZF2001): A randomized, observer-blinded, placebo-controlled trial

BACKGROUND: Heterologous boost vaccination has been proposed as an option to elicit stronger and broader, or longer-lasting immunity. We assessed the safety and immunogenicity of heterologous immunization with a recombinant adenovirus type-5-vectored Coronavirus Disease 2019 (COVID-19) vaccine (Conv...

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Detalles Bibliográficos
Autores principales: Jin, Pengfei, Guo, Xiling, Chen, Wei, Ma, Shihua, Pan, Hongxing, Dai, Lianpan, Du, Pan, Wang, Lili, Jin, Lairun, Chen, Yin, Shi, Fengjuan, Liu, Jingxian, Xu, Xiaoyu, Zhang, Yanan, Gao, George F., Chen, Cancan, Feng, Jialu, Li, Jingxin, Zhu, Fengcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187065/
https://www.ncbi.nlm.nih.gov/pubmed/35617368
http://dx.doi.org/10.1371/journal.pmed.1003953

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